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Depiction
Precursor
3-Methyl-1-(4-methylphenyl)sulfonyl-4-phenylpiperidine-4-carboxylic acid
CC1CN(CCC1(C(O)=O)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)C
6 steps
Depiction
Dead-End Product
Succinyl-carboxylic acid
C(CCC(=O)C(=O)O)(=O)C(O)=O
Depiction
Upstream Precursor
Benzyl 3-methyl-4-phenyl-1-(p-tolylsulphonyl)piperidine-4-carboxylate
CC1CN(CCC1(C2=CC=CC=C2)C(=O)OCC3=CC=CC=C3)S(=O)(=O)C4=CC=C(C=C4)C
Depth 1
Depiction
Product
3-Methyl-1-(4-methylphenyl)sulfonyl-4-phenylpiperidine-4-carboxylic acid
CC1CN(CCC1(C(O)=O)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)C
Depiction
Upstream Precursor
trans-(1)-3-Methyl-4-phenyl-1-(p-tolylsulphonyl)piperidine-4-carbonyl chloride
C[C@H]1CN(CC[C@]1(C2=CC=CC=C2)C(=O)Cl)S(=O)(=O)C3=CC=C(C=C3)C
Depth 1
Depiction
Product
3-Methyl-1-(4-methylphenyl)sulfonyl-4-phenylpiperidine-4-carboxylic acid
CC1CN(CCC1(C(O)=O)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)C
Depiction
Upstream Precursor
3-Methyl-4-phenyl-1-(p-tolylsulphonyl)piperidine-4-carbonitrile
CC1CN(CCC1(C#N)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)C
Depth 1
Depiction
Product
3-Methyl-1-(4-methylphenyl)sulfonyl-4-phenylpiperidine-4-carboxylic acid
CC1CN(CCC1(C(O)=O)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)C
Depiction
Upstream Precursor
CC1CN(CCC1(C2=CC=CC=C2)C(=O)OCC3=CC=C(C(=C3)O)O)S(=O)(=O)C4=C…
Depth 1
Depiction
Product
3-Methyl-1-(4-methylphenyl)sulfonyl-4-phenylpiperidine-4-carboxylic acid
CC1CN(CCC1(C(O)=O)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)C
Depiction
Upstream Precursor
CC1CN(CCC1(C2=CC=CC=C2)C(=O)OCC3=CC=C(C=C3)O)S(=O)(=O)C4=CC=C…
Depth 1
Depiction
Product
3-Methyl-1-(4-methylphenyl)sulfonyl-4-phenylpiperidine-4-carboxylic acid
CC1CN(CCC1(C(O)=O)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)C
Depiction
Upstream Precursor
CC1CN(CCC1(C2=CC=CC=C2)C(=O)OCC3C(C(C(=O)C=C3)O)Cl)S(=O)(=O)C…
Depth 1
Depiction
Product
3-Methyl-1-(4-methylphenyl)sulfonyl-4-phenylpiperidine-4-carboxylic acid
CC1CN(CCC1(C(O)=O)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)C
Depiction
Upstream Precursor
CC1CN(CCC1(C2=CC=CC=C2)C(=O)OCC3=CC(=C(C=C3)O)Cl)S(=O)(=O)C4=…
Depth 1
Depiction
Product
3-Methyl-1-(4-methylphenyl)sulfonyl-4-phenylpiperidine-4-carboxylic acid
CC1CN(CCC1(C(O)=O)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)C
Depiction
Upstream Precursor
CC1CN(CCC1(C2=CC=CC=C2)C(=O)OCC3C=CC(=O)C(C3O)Cl)S(=O)(=O)C4=…
Depth 1
Depiction
Product
3-Methyl-1-(4-methylphenyl)sulfonyl-4-phenylpiperidine-4-carboxylic acid
CC1CN(CCC1(C(O)=O)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)C
Depiction
Upstream Precursor
CC1CN(CCC1(C2=CC=CC=C2)C(=O)OCC3C=CC(=O)C=C3)S(=O)(=O)C4=CC=C…
Depth 1
Depiction
Product
3-Methyl-1-(4-methylphenyl)sulfonyl-4-phenylpiperidine-4-carboxylic acid
CC1CN(CCC1(C(O)=O)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)C
Depiction
Upstream Precursor
CC1CN(CCC1(C2=CC=CC=C2)C(=O)OCC(C=CC(=O)O)=CC(O)=O)S(=O)(=O)C…
Depth 1
Depiction
Product
3-Methyl-1-(4-methylphenyl)sulfonyl-4-phenylpiperidine-4-carboxylic acid
CC1CN(CCC1(C(O)=O)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)C
Depiction
Precursor
3-Methyl-1-(4-methylphenyl)sulfonyl-4-phenylpiperidine-4-carboxylic acid
CC1CN(CCC1(C(O)=O)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)C
Depth 2
Depiction
Downstream Successor
2-Hydroxyhexa-2,4-diendioic acid
C(=CC=CC(=O)O)(C(O)=O)O
Depiction
Precursor
3-Methyl-1-(4-methylphenyl)sulfonyl-4-phenylpiperidine-4-carboxylic acid
CC1CN(CCC1(C(O)=O)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)C
Depth 1
Depiction
Downstream Successor
p-Toluenesulfonic acid
C1=CC(=CC=C1C)S(=O)(=O)O
Depiction
Precursor
3-Methyl-1-(4-methylphenyl)sulfonyl-4-phenylpiperidine-4-carboxylic acid
CC1CN(CCC1(C(O)=O)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)C
Depth 3
Depiction
Downstream Successor
2,3-Dihydroxyhexa-2,4-dienedioic acid
OC(=C(C=CC(=O)O)O)C(O)=O
Depiction
Precursor
3-Methyl-1-(4-methylphenyl)sulfonyl-4-phenylpiperidine-4-carboxylic acid
CC1CN(CCC1(C(O)=O)C2=CC=CC=C2)S(=O)(=O)C3=CC=C(C=C3)C
Depth 3
Depiction
Downstream Successor
2-Chloro-5-hydroxyhexa-2,4-dienedioic acid
C(=CC=C(O)C(=O)O)(Cl)C(O)=O
No Original Precursors

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