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Depiction
Upstream Precursor
methyl 4-hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide
CN1C(=C(C2=CC=CC=C2S1(=O)=O)O)C(=O)OC
Depth 1
Depiction
Product
4-Hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda~6~,2-benzothiazine-3-carboxylic acid
C(=O)(C1=C(C2=CC=CC=C2S(=O)(=O)N1C)O)O
Depiction
Upstream Precursor
4-Hydroxy-2-methyl-2H-1,2-benzothiazine-3-carboxylic acid ethylester 1,1-dioxide
CCOC(=O)C1=C(C2=CC=CC=C2S(=O)(=O)N1C)O
Depth 1
Depiction
Product
4-Hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda~6~,2-benzothiazine-3-carboxylic acid
C(=O)(C1=C(C2=CC=CC=C2S(=O)(=O)N1C)O)O
Depiction
Upstream Precursor
Piroxicam
CN1C(=C(C2=CC=CC=C2S1(=O)=O)O)C(=O)NC3=CC=CC=N3
Depth 1
Depiction
Product
4-Hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda~6~,2-benzothiazine-3-carboxylic acid
C(=O)(C1=C(C2=CC=CC=C2S(=O)(=O)N1C)O)O
Depiction
Upstream Precursor
Meloxicam
CC1=CN=C(S1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O
Depth 1
Depiction
Product
4-Hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda~6~,2-benzothiazine-3-carboxylic acid
C(=O)(C1=C(C2=CC=CC=C2S(=O)(=O)N1C)O)O
Depiction
Upstream Precursor
Sudoxicam
CN1C(=C(C2=CC=CC=C2S1(=O)=O)O)C(=O)NC3=NC=CS3
Depth 1
Depiction
Product
4-Hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda~6~,2-benzothiazine-3-carboxylic acid
C(=O)(C1=C(C2=CC=CC=C2S(=O)(=O)N1C)O)O
Depiction
Upstream Precursor
Isoxicam
CC1=CC(=NO1)NC(=O)C2=C(C3=CC=CC=C3S(=O)(=O)N2C)O
Depth 1
Depiction
Product
4-Hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda~6~,2-benzothiazine-3-carboxylic acid
C(=O)(C1=C(C2=CC=CC=C2S(=O)(=O)N1C)O)O
Depiction
Upstream Precursor
CN1C(=C(C2=CC=CC=C2S1(=O)=O)O)C(=O)N(C3=CC=CC=[N+]3[O-])O
Depth 1
Depiction
Product
4-Hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda~6~,2-benzothiazine-3-carboxylic acid
C(=O)(C1=C(C2=CC=CC=C2S(=O)(=O)N1C)O)O
Depiction
Precursor
4-Hydroxy-2-methyl-1,1-dioxo-1,2-dihydro-1lambda~6~,2-benzothiazine-3-carboxylic acid
C(=O)(C1=C(C2=CC=CC=C2S(=O)(=O)N1C)O)O
Depth 1
Depiction
Downstream Successor
3,4-Dihydro-2-methyl-4-oxo-2H-1,2-benzothiazine-3-carboxylic Acid-1,1-dioxide
CN1C(C(=O)C2=CC=CC=C2S1(=O)=O)C(=O)O
No Original Precursors

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No Dead-Ends

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