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Depiction
Upstream Precursor
H-152/81
OC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)OC)C)C
Depth 1
Depiction
Product
4-(2,3-Dichlorophenyl)-5-(methoxycarbonyl)-2,6-dimethylnicotinic acid
OC(=O)C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl
Depiction
Upstream Precursor
Felodipine
CCOC(=O)C1=C(NC(=C(C1C2=C(C(=CC=C2)Cl)Cl)C(=O)OC)C)C
Depth 2
Depiction
Product
4-(2,3-Dichlorophenyl)-5-(methoxycarbonyl)-2,6-dimethylnicotinic acid
OC(=O)C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl
Depiction
Upstream Precursor
Dehydrofelodipine
CCOC(=O)C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl
Depth 1
Depiction
Product
4-(2,3-Dichlorophenyl)-5-(methoxycarbonyl)-2,6-dimethylnicotinic acid
OC(=O)C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl
Depiction
Upstream Precursor
3,5-Dimethyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
CC1=C(C(C(=C(N1)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl)C(=O)OC
Depth 2
Depiction
Product
4-(2,3-Dichlorophenyl)-5-(methoxycarbonyl)-2,6-dimethylnicotinic acid
OC(=O)C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl
Depiction
Upstream Precursor
Felodipine M (dehydro-desethyl, methyl ester)
CC1=C(C(=C(C(=N1)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl)C(=O)OC
Depth 1
Depiction
Product
4-(2,3-Dichlorophenyl)-5-(methoxycarbonyl)-2,6-dimethylnicotinic acid
OC(=O)C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl
Depiction
Precursor
4-(2,3-Dichlorophenyl)-5-(methoxycarbonyl)-2,6-dimethylnicotinic acid
OC(=O)C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl
Depth 1
Depiction
Downstream Successor
4-(2-Chlorophenyl)-5-methoxycarbonyl-2,6-dimethylpyridine-3-carboxylic acid
CC1=C(C(=C(C(=N1)C)C(=O)O)C2=CC=CC=C2Cl)C(=O)OC
Depiction
Precursor
4-(2,3-Dichlorophenyl)-5-(methoxycarbonyl)-2,6-dimethylnicotinic acid
OC(=O)C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl
Depth 1
Depiction
Downstream Successor
C(=O)(C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=CC=C2)O)Cl)O
Depiction
Precursor
4-(2,3-Dichlorophenyl)-5-(methoxycarbonyl)-2,6-dimethylnicotinic acid
OC(=O)C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl
Depth 1
Depiction
Downstream Successor
C(=O)(C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=C(C=C2)O)Cl)Cl)O
Depiction
Precursor
4-(2,3-Dichlorophenyl)-5-(methoxycarbonyl)-2,6-dimethylnicotinic acid
OC(=O)C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl
Depth 2
Depiction
Downstream Successor
4-(3-Hydroxyphenyl)-5-methoxycarbonyl-2,6-dimethylpyridine-3-carboxylic acid
Cc1c(c(c(c(n1)C)C(=O)OC)-c2cc(ccc2)O)C(=O)O
Depiction
Precursor
4-(2,3-Dichlorophenyl)-5-(methoxycarbonyl)-2,6-dimethylnicotinic acid
OC(=O)C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl
Depth 1
Depiction
Downstream Successor
C(=O)(C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=CC=C2)Cl)O)O
Depiction
Precursor
4-(2,3-Dichlorophenyl)-5-(methoxycarbonyl)-2,6-dimethylnicotinic acid
OC(=O)C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl
Depth 1
Depiction
Downstream Successor
4-(2,3-Dichlorophenyl)-2,6-dimethylpyridine-3,5-dicarboxylic acid
C(=O)(C1=C(C(=C(N=C1C)C)C(=O)O)C2=C(C(=CC=C2)Cl)Cl)O
Depiction
Precursor
4-(2,3-Dichlorophenyl)-5-(methoxycarbonyl)-2,6-dimethylnicotinic acid
OC(=O)C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl
Depth 1
Depiction
Downstream Successor
4-(3-Chlorophenyl)-5-methoxycarbonyl-2,6-dimethylpyridine-3-carboxylic acid
C(=O)(C1=C(C(=C(N=C1C)C)C(=O)OC)C2=CC(=CC=C2)Cl)O
Depiction
Precursor
4-(2,3-Dichlorophenyl)-5-(methoxycarbonyl)-2,6-dimethylnicotinic acid
OC(=O)C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl
Depth 1
Depiction
Downstream Successor
C(=O)(C1=C(C(=C(N=C1C)C)C(=O)OC)C2C(Cl)=C(Cl)C(=O)C=C2)O
Depiction
Precursor
4-(2,3-Dichlorophenyl)-5-(methoxycarbonyl)-2,6-dimethylnicotinic acid
OC(=O)C1=C(C(=C(N=C1C)C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl
Depth 1
Depiction
Downstream Successor
C(=O)(C1=C(C(=C([N+](=C1C)[O-])C)C(=O)OC)C2=C(C(=CC=C2)Cl)Cl)O
No Original Precursors

No entries were found for this section with the current query and depth.

No Dead-Ends

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